• 
  PSG – Brest

  19 February

• 
  Real Madrid RM – Manchester

  19 February

• 
  PSV – Juventus

  19 February

• 
  Dortmund – Sporting

  19 February

• 
  Union – Millonarios

  21 February

• 
  Once Caldas – Deportivo

  20 February

• 
  Aston Villa – Liverpool

  19 February

• 
  Panathinaikos – Vikingur

  20 February

• 
  Shamrock Rovers – Molde

  20 February

• 
  APOEL – Celje

  20 February

• 
  Real Betis – Gent

  20 February

• 
  Heidenheim – Copenhagen

  20 February

• 
  Viktoria – Ferencvaros

  20 February

• 
  Real – Midtjylland

  20 February

• 
  Anderlecht – Fenerbahce

  20 February

• 
  Ajax – Union

  20 February

• 
  Galatasaray – AZ

  20 February

• 
  Roma – Porto

  20 February

• 
  FCSB – PAOK

  20 February

• 
  Bodoe/Glimt – Twente

  20 February

• 
  Spartak M – Sibir

  20 February

• 
  Lokomotiv – Kunlun RS

  20 February

• 
  Barys – Severstal

  20 February

• 
  Avtomobilist – Amur

  20 February

• 
  Dynamo Msk – Sochi

  19 February

• 
  CSKA – Dinamo Mn

  19 February

• 
  Santos Laguna – Cruz

  20 February

• 
  America – Leon

  20 February

• 
  Lion City Sailors – Muangthong

  20 February

• 
  Jeonbuk – Port

  20 February

• 
  Al-Taawoun – Al-Wakrah

  19 February

• 
  Shabab – Al-Wehdat

  19 February

• 
  Defensa y Justicia – Racing

  20 February

• 
  Laferrere – Dock Sud

  19 February

• 
  Fenix Pilar – Villa

  19 February

• 
  Carlos Alcaraz – Jiri

  20 February

• 
  Newcastle Jets – Brisbane

  21 February

• 
  Palmeiras – Botafogo-SP

  20 February

• 
  RB Bragantino – Mirassol

  20 February

• 
  Sao Paolo – Ponte Preta

  19 February

• 
  Santos-SP – Noroeste

  19 February

• 
  Fortaleza – Vitoria-BA

  20 February

• 
  Sport Recife – Moto Club

  19 February

• 
  Boavista SC – CSA

  19 February

• 
  CSKA 1948 – Botev Vratsa

  21 February

• 
  Deportivo – Vancouver

  21 February

• 
  Motagua – Cincinnati

  20 February

• 
  Kansas City – Inter

  20 February

• 
  Antigua GFC – Seattle

  20 February

• 
  Herediano – Real

  20 February